Abstract

Small intestine bacterial overgrowth is also known as the blind loop, stagnant loop, or stasis syndrome, the syndrome associated with the excessive numbers of bacteria in the proximal small intestine. The pathophysiology of this condition involves competition between the bacteria and the human host for ingested nutrients. This leads to intraluminal bacterial catabolism of nutrients, often with production of and inury to the enterocyte. A complex array of clinical symptoms ensues, resulting in intestinal malabsorption, weight loss, and malnutrition. These symptoms and signs can be reversed with appropriate antimicrobial therapy.

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