THE CHANGES OF SOME INDICES OF BIOCHEMICAL STATUS IN COWS WITH METABOLIC DISORDERS

Abstract

Under present-day conditions of market economy, the requirements to the quality and quantity of livestock products increase significantly, and this leads to significant intensification of production and, as a consequence, to the development of metabolic disorders including ketosis in highly productive cows. The research goal was to study protein and mineral metabolism in ketotic cows before and after calving. The studies were conducted on the Training Farm «Prigorodnoye» in the City of Barnaul in autumn and winter in comparable Black-Pied cows. Two groups of cows were formed: the trial group consisted of ketotic cows; the control group consisted of apparently healthy cows. These cows underwent clinical and biochemical examination. The biochemical study of blood determined the following: total protein, albumins, alpha-globulins, beta-globulins, gamma-globulins, total calcium, inorganic phosphorus and ketone bodies. The biochemical blood tests were run 4 times: 2 months and 1 month before calving, and in 10 days and in 1 month after calving. It was found that the change of protein metabolism indices in ketotic cows showed a profound disorder of the protein synthesis function of liver both before and after calving. The level of total calcium in the blood of ketotic cows was characterized by lower values as compared to that in healthy comparable cows. At the same time, the dynamics of inorganic phosphorus concentration change did not have significant differences between ketotic and healthy cows. Total calcium content in ketotic cows increased one month before calving while in apparently healthy cows this index increased after calving only. The concentration of ketone bodies in the blood of ketotic cows was significantly higher than that of apparently healthy cows throughout the study.