Abstract
Acupuncture is used to treat a wide variety of eye diseases, although there is little evidence about the effects of acupuncture treatment and the mechanisms responsible for them. Foot acupuncture treatment has effects in both mice and humans. The purpose of this study was to investigate the effects of acupuncture treatment on ocular blood flow in mice. We evaluated ocular blood flow in C57BL/6J mice after foot acupuncture treatment using laser speckle flowgraphy. The mean blur rate, which is an index of blood flow velocity, was increased in the foot acupuncture group. Our results showed that, after 3 minutes' foot acupuncture, ocular blood flow was significantly increased in both the blood vessels and tissue of the eye in C57BL/6J mice. Thus, performing acupuncture in mice might help to determine its effects. Furthermore, acupuncture is considered to be a possible treatment for ocular disease.
Highlights
Acupuncture is a traditional Chinese medicine, which has been used for over 5,000 years [1]
Increased Ocular Blood Flow Was Seen in the Mice after Foot Acupuncture Treatment
laser speckle flowgraphy (LSFG) was used to analyze blood flow in the choroidal and retinal regions based on examinations of the mean blur rate (MBR)
Summary
Acupuncture is a traditional Chinese medicine, which has been used for over 5,000 years [1] It has a variety of effects on degenerative and psychosomatic diseases involving cerebral or peripheral ischemia [2,3,4,5,6]. Electrostimulation improved the vestibulo-ocular reflexes of rabbits with vertebrobasilar insufficiency, by inducing improvements in basilar artery hemodynamics, inner ear blood flow, and blood viscosity [7]. It is still poorly understood as a potential therapy for ocular disease because there is a lack of reliable evidence about its effects. E aim of this study was to investigate the changes in blood vessel and tissue blood flow seen in the eyes of mice after foot acupuncture treatment
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