The Changes are Incorporated in Red Color Font Transcutaneous Ultrasonographic Assessment of Oral Submucous Fibrosis: A Preliminary Study

Abstract

Oral submucous fibrosis (OSMF) is well recognized as one of the most common potentially premalignant conditions of the oral mucosa in India related to chewing of areca nut products and characterized by mucosal rigidity of varying intensity caused by fibroelastic changes of the juxta-epithelial layer, resulting in a progressive inability to open the mouth. The present study aimed to measure submucosal thickness by high frequency ultrasonography (USG) in cases and controls and to correlate this with clinical and histological severity of the disease. We conducted a hospital-based cross sectional study of 20 subjects who were clinically and histopathologically proven to have OSMF (cases) and 20 controls matched for age, sex and body mass index. Transcutaneous imaging of the buccal and labial submucosa was performed and the values were correlated with clinical stage and histological grade of the disease. Cases had increased submucosal thickness when compared to controls at all measured sites. The echogenicity pattern of cases showed areas of irregular hyperechoic linear streaks due to fibrotic submucosal deposits. In contrast, the submucosa of controls appeared as a hypoechoic band. To the best of our knowledge, this is the first study to use USG to measure the thickness of submucosal fibrosis in OSMF.