Abstract
In the complex treatment of patients with tuberculosis with destruction of pulmonary tissue in the presence of drug-resistant pathogen in 10.2 % of cases it is necessary to resort to surgery in the form of resection or pulmonectomy. In the postoperative period, there are cases of progression of a specific process in the lungs with the formation of destruction. In such a situation, the optimal choice of treatment strategy is endoscopic valve bronchomalacia (ECB) with maximum preservation of functioning lung tissue. The aim of this work is to study the dynamics of ventilation and gas exchange function of the lungs in patients with acute pulmonary tissue destruction after surgery. The study revealed a change in the functional state of the lungs in 56 % of cases: negative in 39 % of patients and positive — in 17 %. The nature of the changes associated with the initial state of the bronchopulmonary apparatus and the characteristics of drug resistant. Deterioration of function is more often observed in a two-sided process and/or in the presence of two or more caverns. The initial state of the lung ventilation capacity and the presence of signs of restrictive disorders have the opposite effect on the functional outcome of bronchoblocation: at normal values of FEV1 and ESRD IS accompanied by more frequent broncho-obstructive disorders and deterioration of gas exchange rates than at their reduced values. The same paradoxical functional dependence of the dynamics can be traced in the volume «off» when drug resistant and its effectiveness.
Highlights
necessary to resort to surgery in the form
The aim of this work is to study the dynamics of ventilation and gas exchange function of the lungs
The study revealed a change in the functional state of the lungs
Summary
Резюме В комплексном лечении больных туберкулезом с деструкцией легочной ткани при наличии лекарственно резистентного возбудителя в 10,2 % случаев приходится прибегать к хирургическому вмешательству в виде резекции или пульмонэктомии. Цель настоящей работы — изучение динамики вентиляционной и газообменной функции легких на фоне ЭКББ у пациентов с обострением деструкции легочной ткани после оперативного лечения. Цель исследования — выявление качественных и количественных изменений вентиляционной и газообменной функции легких при эндоскопической клапанной бронхоблокации у больных, перенесших ранее резекцию легкого по поводу фиброзно-кавернозного лекарственно-устойчивого туберкулеза (ФКТ). При комплексной оценке функциональной динамики к улучшению/ухудшению относили увеличение/снижение двух и более показателей легочной вентиляции и/или газообмена (кроме РаСО2). Таблица 1 Частота и выраженность функциональной динамики при ЭКББ у оперированных больных с деструктивным туберкулезом легких (n=41).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
