Abstract
Stroke is time critical.1 Commencement of ultra-early treatments in the prehospital setting holds the potential to limit neuronal damage and improve outcome. However, stroke is also a heterogeneous condition and its diagnosis requires the use of neuroimaging. Therefore, any prehospital intervention in patients with suspected stroke must also be safe for patients with intracerebral haemorrhage or ischaemic stroke.2 The FAST-MAG trial showed the feasibility and safety of large-scale prehospital drug trials, despite its neutral findings.
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