Abstract
Biofilms containing foodborne pathogens can adhere to food ingredients or food processing equipment. Due to their enhanced resilience to cleaning and chance of cross-contamination, there is an increased risk of food poisoning to consumers. The life course of biofilms is generally thought to be regulated by a quorum sensing (QS) system by secreted autoinducing peptides (AIPs). Recent studies have revealed that small non-coding RNA (sRNA) also plays an important role in regulating biofilm formation at the post-transcriptional level. Moreover, sRNA can act as an intermediate regulating hub between the quorum sensing system and biofilm. This review summarizes the latest findings on sRNA in biofilms of common foodborne pathogens and their potential impact. We also highlight the different mechanism of cascade regulation of sRNA and QS system in biofilm formation in several typical foodborne pathogens. In this process, sRNA responds to dynamic external environmental signals finely and accurately, and can feedback information on the bacterial cell environment to modify the QS system. These findings will deepen our understanding of biofilm formation and provide new perspectives for eliminating biofilm of foodborne pathogens based on the cascade regulation of small RNA and QS for developing biofilm-free food-processing systems.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.