Abstract
At present, carry-over research in mycotoxins experiences a change in focus. We reviewed the state-of-art knowledge regarding carry-over in aflatoxins, ochratoxin A, Fusarium toxins, patulin, ergot and citrinin. The common cooccurrence of mycotoxins demands for employment of multi-toxin analysis and poses a new challenge in reliable health hazard assessment. Synergies in adverse mycotoxin effects call for a revision of various guidance levels in feed. We found a lack of risk assessment regarding carry-over of rare mycotoxins and metabolites usually considered negligible.
Highlights
Mycotoxins can be seen as natural contaminants which can occur in food, originating from the environment, processing or packaging
We reviewed the state-of-the-art knowledge regarding carry-over in aflatoxins, ochratoxin A, Fusarium toxins, patulin, ergot and citrinin
Threshold limits concerning human exposure were published by the Joint WHO/FAO Expert Committee on Food Additives (JECFA) in 2001, advising a Provisional Maximum Tolerable Daily Intake (PMTDI) of 2 μg·kg–1 BW
Summary
Mycotoxins can be seen as natural contaminants which can occur in food, originating from the environment, processing or packaging. Albeit aflatoxins had been examined since 1981, they continued to stay in focus for a long time apart from few studies on ochratoxin A and some Fusarium toxins It was not until the beginning of the 1990s that other groups of mycotoxins were included in the studies. The first part introduces in detail each of these mycotoxins by presenting basic data including natural occurrence, adverse health effects, biotransformation, known data of carry-over to livestock animals and statutory limits set for feed or food stuffs. The second part evaluates carry-over study results, but critically deals with current mycotoxin feed and food legislation summarizing latest research achievements in the fields of bioavailability, biotransformation and synergistic toxin interactions, and pointing out weakpoints in current diagnostic tools and surveillance programmes
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
