The cardiopathic features and analysis of risk factors in the elderly diabetic

Abstract

Objectives To investigate the cardiac condition of the diabetic patients in our hospital and to seek for the new diagnostic method of warning its cardiovascular complications in early times. Methods 274 diabetic patients in our hospital from January in 2004 to July in 2008 were divided into 2 groups: group A (94 patients whose age ranged from 31 to 59) and group B (180 patients whose age ranged from 60 to 90). The height, weight, blood pressure, lipid were recorded, the ejection fraction (EF), fractional shortening (FS), diameter of left ventricle in late diastolic stage (LVEDd), the thickness of the ventricular septa (IVSD) and the posterior wall of the right ventricle in late diastolic stage (LVPWd) were recorded. Left ventricular mass index (LVMI) and relative wall thickness (RWT) were calculated. High-sensitive C-reactive protein (HsCRP) and TNF-α were recorded. Multifactor linear regression analysis was made based on the comparison and contrast between all indexes to analyze the correlations between LVMI, RWT and the positive indexes. Results No obvious differences of the height, weight, blood glucose, lipid, blood pressure, ejection fraction (EF), FS, were observed, however, distinctive increases of LVMI (t=−2.022, P=0.044), RWT (t=−3.512, P=0.001), High-sensitive C-reactive protein (t=−2.378, P=0.018) and TNF-α (t=−4.724, P=0.000) were found in group A than those in group B (P<0.05). According to the results of multifactor linear regression analysis, age (LVMIβ=0.137, RWTβ=0.286), course of disease (LVMIβ=0.141, RWTβ=0.295), high-sensitivity C-reactive protein (LVMIβ=0.165, RWTβ=0.382) and TNF-α (LVMIβ=0.161, RWTβ=0.293) are closely related to LVMI and RWT. Conclusion With the increase of age, the diabetic patients are susceptive to cardiac hypertrophy. The specific change of LVMI and RWT are increased, High-sensitive C-reactive protein and TNF-α detection may effectively make a warning of this pathological process in early times. Objectives To investigate the cardiac condition of the diabetic patients in our hospital and to seek for the new diagnostic method of warning its cardiovascular complications in early times. Methods 274 diabetic patients in our hospital from January in 2004 to July in 2008 were divided into 2 groups: group A (94 patients whose age ranged from 31 to 59) and group B (180 patients whose age ranged from 60 to 90). The height, weight, blood pressure, lipid were recorded, the ejection fraction (EF), fractional shortening (FS), diameter of left ventricle in late diastolic stage (LVEDd), the thickness of the ventricular septa (IVSD) and the posterior wall of the right ventricle in late diastolic stage (LVPWd) were recorded. Left ventricular mass index (LVMI) and relative wall thickness (RWT) were calculated. High-sensitive C-reactive protein (HsCRP) and TNF-α were recorded. Multifactor linear regression analysis was made based on the comparison and contrast between all indexes to analyze the correlations between LVMI, RWT and the positive indexes. Results No obvious differences of the height, weight, blood glucose, lipid, blood pressure, ejection fraction (EF), FS, were observed, however, distinctive increases of LVMI (t=−2.022, P=0.044), RWT (t=−3.512, P=0.001), High-sensitive C-reactive protein (t=−2.378, P=0.018) and TNF-α (t=−4.724, P=0.000) were found in group A than those in group B (P<0.05). According to the results of multifactor linear regression analysis, age (LVMIβ=0.137, RWTβ=0.286), course of disease (LVMIβ=0.141, RWTβ=0.295), high-sensitivity C-reactive protein (LVMIβ=0.165, RWTβ=0.382) and TNF-α (LVMIβ=0.161, RWTβ=0.293) are closely related to LVMI and RWT. Conclusion With the increase of age, the diabetic patients are susceptive to cardiac hypertrophy. The specific change of LVMI and RWT are increased, High-sensitive C-reactive protein and TNF-α detection may effectively make a warning of this pathological process in early times.