Abstract
SummaryA very low cyclic GMP concentration (5 × 10–11M) causes the actively “cycling” lymphoblasts in isolated rat thymic lymphocyte populations to start synthesizing DNA by a calcium-independent process. These stimulated cells are able to progress subsequently through the DNA-synthetic phase and enter mitosis. The possible significance of the cyclic GMP-induced stimulatory action in the regulation of lymphoblast proliferation is discussed. An attempt is also made to interrelate the similar actions of cyclic GMP and cyclic AMP.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
