The Caenorhabditis elegans Centrosomal Protein SPD-2 Is Required for both Pericentriolar Material Recruitment and Centriole Duplication

Abstract

(Current Biology 14, 863–873; May 25, 2004) The sequences of the oligos used to generate SPD-2 dsRNA as indicated in the online supplementary material accompanying this paper were incorrect. The correct sequences of the primers used are as follows (T3 and T7 promoter sequences are underlined):Forward:aattaaccctcactaaaggTGCATGCGAATAAGACGAAGReverse:taatacgactcactataggTTGCGGACACAGAAAACAAA This error does not change any of the results presented in the paper. The authors would like to apologize to their colleagues for any inconvenience this may have caused. The Caenorhabditis elegans Centrosomal Protein SPD-2 Is Required for both Pericentriolar Material Recruitment and Centriole DuplicationPelletier et al.Current BiologyMay 25, 2004In BriefBackground: The centrosome is composed of a centriole pair and pericentriolar material (PCM). By marking the site of PCM assembly, the centrioles define the number of centrosomes present in the cell. The PCM, in turn, is responsible for the microtubule (MT) nucleation activity of centrosomes. Therefore, in order to assemble a functional bipolar mitotic spindle, a cell needs to control both centriole duplication and PCM recruitment. To date, however, the molecular mechanisms that govern these two processes still remain poorly understood. Full-Text PDF Open Archive