Abstract
The CA3 region of the hippocampus: how is it? What is it for? How does it do it?
Highlights
The hippocampus, in the temporal lobe, is phylogenetically one of the oldest parts of the brain and forms part of the limbic system
The seven reviews and four research articles are organized to follow neuronal information flowing from the dentate gyrus to the CA3 associative network
With a clear GABAergic phenotype, granule cells have small somata, few dendritic branches and axons often terminate as growth cones in the CA3 region
Summary
The hippocampus, in the temporal lobe, is phylogenetically one of the oldest parts of the brain and forms part of the limbic system. Recurrent axon collaterals of CA3 pyramidal cells ramify extensively making excitatory contacts with neighboring excitatory and inhibitory neurons (Lorente de Nó, 1934). The seven reviews and four research articles are organized to follow neuronal information flowing from the dentate gyrus to the CA3 associative network. SISSA, Trieste and European Brain Research Inst, Rome) studied immature granule cells at P0–P3.
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