The C-reactive protein/albumin ratio as a predictor of mortality in sepsis patients in ICU H. Adam Malik Hospital Medan and connected to SOFA score

Abstract

Background: Sepsis is a major cause of mortality in the ICU. Therefore, estimating patient mortality from ICU treatment rooms is very important. Organ failure is one of the causes of high mortality rates for ICU patients. Accordingly we need a biomarker that can predict the mortality in which way it can reflect the concept of inflammation from sepsis. Based on that reason, this study is aimed at looking at the CRP / Albumin ratio associated with the SOFA score to predict mortality in septic patients.Methods: This study took the blood samples of 58 patients who were being treated at the ICU. Samples were checked for CRP and Albumin on day 1 and 3. At the same time, the SOFA scores and CRP / Albumin ratios were also calculated on day 1 and 3. Finally, the study was conducted after obtaining ethical approval and informed consent.Result And Discussion: 30 men (51,7%) and 28 women (48,3%) with the youngest was 16 years old and the oldest was 65 years old. The CRP / Albumin ratio for day 1 did not have a significant relationship with day 1 of the SOFA scores (P>0.05) and The CRP / Albumin ratio for day 3 have a significant relationship with day 3 of the SOFA scores (P<0.05)Conclusion and Suggestion: The CRP / Albumin ratio and SOFA score can predict the mortality of septic patients. Further research is needed to see the CRP / Albumin ratio and SOFA score as a mortality predictor for septic patients.