Abstract
ObjectivesUsing the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016.MethodsWe modelled headache disorders using DisMod-MR 2.1 Bayesian meta-regression tool to ensure consistency between prevalence, incidence, and remission. Years lived with disability (YLDs) were calculated by multiplying prevalence and disability weight (DW) of migraine and tension-type headache (TTH). We assumed primary headache disorders as non-fatal, so their YLD is equal to disability-adjusted life years (DALYs).ResultsMigraine and TTH were the second and twentieth leading causes of YLDs in EMR. Between 1990 and 2016, the absolute YLD numbers of migraine and TTH increased from 2.3 million (95% uncertainty interval (UI): 1.5–3.2) to 4.7 million (95%UI: 3–6.5) and from 383 thousand (95%UI: 240–562) to 816 thousand (95%UI: 516–1221), respectively. During the same period, age-standardised YLD rates of migraine and TTH in EMR increased by 0.7% and 2.5%, respectively, in comparison to a small decrease in the global rates (0.2% decrease in migraine and TTH). The bulk of burden due to headache occurred in the 30–49 year age group, with a peak at ages 35–44 years. The age-standardised YLD rates of both headache disorders were higher in women with female to male ratio of 1.69 for migraine and 1.38 for TTH. All countries of the EMR except for Somalia and Djibouti had higher age-standardised YLD rates for migraine and TTH in compare to the global rates. Libya and Saudi Arabia had the highest increase in age-standardised YLD rates of migraine and TTH, respectively.ConclusionThe findings of this study show that primary headache disorders are a major and a growing cause of disability in EMR. Since 1990, burden of primary headache disorders has constantly been higher in EMR compared to rest of the world, which indicates that health systems in EMR must focus further on developing and implementing preventive and management strategies to control headache.
Highlights
Headache, with the global prevalence of 47%, is one of the most common neurological disorders [1] Headache can be a secondary symptom of an underlying conditions; in most cases it is a primary and non-fatal disorder [2, 3]
Estimation of years lived with disability (YLDs) and prevalence of diseases were among the main objectives of Global Burden of Disease Study (GBD) [4]
We reported the prevalence and burden of primary headache disorders in Eastern Mediterranean Region (EMR) countries from 1990 to 2016 using data and methods of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016
Summary
With the global prevalence of 47%, is one of the most common neurological disorders [1] Headache can be a secondary symptom of an underlying conditions (e.g. intracranial neoplasms, epileptic seizures, and intracranial infections); in most cases it is a primary and non-fatal disorder [2, 3]. Primary headaches such as migraine, tension-type headache (TTH), and cluster headache, non-fatal, cause substantial disability and economic cost [4,5,6,7]. GBD 2016, provided more accurate estimations of prevalence and burden of headache by countries, regions, and super regions [4]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
