Abstract

BackgroundBurden of disease studies have been implemented in many countries using the Disability-Adjusted Life Year (DALY) to assess major health problems. Important objectives of the study were to quantify intra-country differentials in health outcomes and to place the United States situation in the international context.MethodsWe applied methods developed for the Global Burden of Disease (GBD) to data specific to the United States to compute Disability-Adjusted Life Years. Estimates are provided by age and gender for the general population of the United States and for each of the four official race groups: White; Black; American Indian or Alaskan Native; and Asian or Pacific Islander. Several adjustments of GBD methods were made: the inclusion of race; a revised list of causes; and a revised algorithm to allocate cardiovascular disease garbage codes to ischaemic heart disease. We compared the results of this analysis to international estimates published by the World Health Organization for developed and developing regions of the world.ResultsIn the mid-1990s the leading sources of premature death and disability in the United States, as measured by DALYs, were: cardiovascular conditions, breast and lung cancers, depression, osteoarthritis, diabetes mellitus, and alcohol use and abuse. In addition, motor vehicle-related injuries and the HIV epidemic exacted a substantial toll on the health status of the US population, particularly among racial minorities. The major sources of death and disability in these latter populations were more similar to patterns of burden in developing rather than developed countries.ConclusionEstimating DALYs specifically for the United States provides a comprehensive assessment of health problems for this country compared to what is available using mortality data alone.

Highlights

  • Burden of disease studies have been implemented in many countries using the DisabilityAdjusted Life Year (DALY) to assess major health problems

  • The study was patterned after the Global Burden of Disease (GBD) and applied methods used in the GBD analysis to compute years of life lost due to premature mortality (YLL), years of life lost due to disability (YLD), and disability-adjusted life years (DALYs)

  • YLL, YLD and DALYs for the 73 causes included in the US Burden of Disease and Injury study (USBODI) by age, gender and race are provided [see Additional file 4]

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Summary

Introduction

Burden of disease studies have been implemented in many countries using the DisabilityAdjusted Life Year (DALY) to assess major health problems. The study essentially applied the methods used in the Global Burden of Disease analysis to data specific to the United States in order to calculate DisabilityAdjusted Life Year (DALY) values for major health conditions and risk factors [1]. The genesis of the US Burden of Disease and Injury study (USBODI) was the release of the 1993 World Development Report: Investing in Health published by the World Bank. This landmark report in international health policy introduced a new summary measure of population health – the Disability-Adjusted Life Year (DALY) [2].

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