The Brain Structure and Intrinsic Characters of Falsification Thinking in Conditional Proposition Testing.

Abstract

Wason's selection task (WST) as a representative of the field of conditional proposition testing has been explored by multiple disciplines for more than 50 years, but the neural basis of its key falsification thinking remains unclear. Considering that the accuracy of individuals in WST has stability over time, we believe that falsification thinking has a specific brain structural basis and intrinsic neural characteristics. To test this hypothesis, we studied individuals who were able to complete the WST using T1-weighted MRI (using voxel-based morphology (VBM) analysis) and resting electroencephalogram (EEG) (using microstate analysis, which can reflect stable cognitive characteristics of individuals) techniques. First, VBM analysis found that, compared with the verification group, the gray matter volume (GMV) of the left inferior temporal gyrus and the right superior temporal region of the falsification group was larger, whereas the GMV in the cerebellum of the verification group was significantly larger than that of the falsification group. Subsequently, the results of the microstate analysis of the resting EEG data showed that the contribution of class A of the falsification group, which is closely related to the language network, is significantly higher than that of the verification group. Our structural MRI and resting EEG results consistently show that the structure and intrinsic activity pattern of the temporal lobe in individuals with falsification thinking are specific. Furthermore, the findings may provide potential insights into the role of the temporal lobe (which is also a brain region of language processing) in thought.