The Brain and Hypothermia-From Aristotle to Targeted Temperature Management.

Abstract

1Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, and Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 2Department of Pediatrics, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, and Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 3Department of Anesthesiology, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, and Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 4Department of Bioengineering, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, and Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. 5Department of Clinical and Translational Science, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, and Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. Supported, in part, by National Institutes of Health/NINDS grant to Dr. Jackson (1R21NS088145). Dr. Kochanek is a co-patent holder for U.S. patent 8,628,512 B2, Title: Method of inducing EPR following cardiopulmonary arrest, filing date; June 22, 2005, Investors P.M. Kochanek, S.A. Tisherman, X. Wu, S.W. Stezoski, L. J. Yaffe. Drs. Kochanek and Jackson are co-provisional patent holders for U. S. Invention Disclosure: Title: Method to improve neurologic outcomes in temperature managed patients, Application No: 62/164, 2005, Country: United States, Innovators: Travis C. Jackson (University of Pittsburgh) and Patrick M. Kochanek (University of Pittsburgh). Dr. Kochanek is supported by National Institutes of Health (NIH), National Institutes of Neurological Disorders and Stroke (NINDS) grant NS070003 and U.S. Army Grants WH81XWH-10-0623 and WH81XWH-14-2-0018. Dr. Jackson is supported by an American Heart Association National Scientist Development Grant and a grant from the NIH/NINDS (NS088145). Dr. Jackson received funding from the National Neurotrauma Society/Invited Speaker/$500 Travel Reimbursement for a presentation on this topic. For information regarding this article, E-mail: [email protected]