Abstract
Due to the semi-permeable membrane and biocompatibility, microcapsules have a very promising future in cell transplantation, drug carrier and large-scale cell culture. However, the current design prevents it from playing a role in tissue scaffold. To address this pitfall, we invented a self-assembled botryoidal microcapsule by means of electrostatic interactions. The diameter of the scaffold was adjustable between 1 and 5cm, while that of the standard microcapsule is ordinarily 500µm. Tests showed that it had better mechanical strength, as well as characteristics of biocompatibility and permeability. A botryoidal microcapsule is also effective at blocking the entrance of IgG and has the potential to function both as a favorable carrier and as a scaffold for artificial organs.
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