Abstract

The purpose of this paper is (1) to present additional hematological abnormalities seen in studies of bone marrow of schizophrenic patients; (2) to give evidence for the genealogy of the abnormal cells which have been described in the peripheral blood of schizophrenic patients<sup>1</sup>; and (3) to suggest that these abnormal cells may be related to the abnormal blood proteins found in psychiatric patients.<sup>2</sup>Elsewhere we have described the abnormal white blood cells in schizophrenia as falling into three main types: the first representing abnormal lymphocytes; the second seeming to belong to the reticulum cell series; and the least numerous, the third type, being multinucleated giant cells.<sup>1</sup>Kamp found that in comparison to normal the nucleus of the lymphocyte was deeper staining and the chromatin lacked an organized pattern.<sup>3</sup> Materials and Methods <i>Patients</i>.—We studied seven male, chronic

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