Abstract
This text contains material from a series of lectures by distinguished scientists and clinicians who participated in the Advanced Study Institutes series on blood-retinal barriers that was held in Espinho, Portugal, in September 1979. The book is divided into the following parts: general aspects of membrane permeability; sites and functions of the blood-brain and blood-retinal barriers; transport at the blood-brain and blood-retinal barriers; methods of evaluation of the blood-retinal barriers, including vitreous fluorophotometry and fluorescein angiography; pathologic characteristics of the blood-retinal barriers; and clinical importance of alterations of the blood-retinal barriers. Ophthalmologists will find the first half of this book highly technical. The authors deal with current concepts having to do with the structure and function of cell membranes; the biophysical aspects of membrane permeability; the relationship of cerebral endothelium and astrocytic membranes; cerebral vascular permeability after osmotic changes; sites and functions of blood-retinal barriers, as well as alterations of
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