Abstract
In 1983 the author and his colleagues at Nimbus Medical embarked on a bold research and development journey to adapt a miniature axial flow pump to the pumping of blood for use as a left ventricular assist device (LVAD). In spite of the harsh criticism of skeptics the author and Nimbus surmounted major technical barriers and paradigms and achieved the first successful clinical use of an axial flow blood pump, the Hemopump, as an LVAD. This sentinel event laid the foundation for the numerous axial flow blood pumps now in development or clinical use. The author will discuss the key technical developments related to hemolysis, thromboresistance and durability and some important non-intuitive lessons related to the physiology and clinical use of the Hemopump. Finally, he will discuss the role for finite element analysis and computer modeling in the design of axial flow blood pumps and his perspective on the clinical role for such pumps for minimally invasive applications.
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