Abstract

The Biotin Connection: Severo Ochoa, Harland Wood, and Feodor Lynen

Highlights

  • Unique circumstances sometimes bring us into contact with individuals who will profoundly influence us, in our formative years

  • My connection developed through the B vitamin, biotin, and its role in the reactions catalyzed by a family of biotin-dependent enzymes, notably carboxylases

  • It is a curiosity that nature has brought together within the hen’s egg the richest source of biotin in the yolk and in the white, a “toxic” factor, avidin, which when fed to animals causes biotin deficiency

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Summary

Introduction

Unique circumstances sometimes bring us into contact with individuals who will profoundly influence us, in our formative years. The Biotin Connection: Severo Ochoa, Harland Wood, and Feodor Lynen In this article I would like to reflect on the circumstances that brought me into contact with three great biochemists, Severo Ochoa (1), Harland Wood (2), and Feodor Lynen (3).

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