The biosensor application in cancer detections: A review

Abstract

Cancer has a higher possibility to be cured if the cancer can be detected earlier. However, many malignancies are currently diagnosed only after they have spread throughout the body due to late diagnosis. Current devices have limitations to detect early cancer cells as the huge variations in the signal and limiting repeatability and sensitivity. Thus, more specific, and sensitive device of biosensor is required urgently for early cancer cells detection. The design and advancement of biosensor technology has become a focal point in recent years due to a broad variety of biosensor applications of cancer detections. These devices convert the genomic materials into an electric signal that can be identified by recognizing a specific biological analyte. In addition, the recent application of biosensors together with nanomaterials has constituted an excellent strategy in cancer monitoring and detection. This review recaps the latest literature search insights the biosensors development and application on their biological recognitions. Finally, the up-to-date approaches applied in biosensors using the nanomaterials and micro-technologies as advancement in detecting various cancers are highlighted in this review paper.