Abstract
It has been demonstrated by Rowntree, Clark, Steinberg and Hanson (1) that daily intraperitoneal injections of 1 cc. of a potent thymus extract into successive generations of albino rats of the Wistar strain results in an accruing acceleration in the rate of growth and development of the offspring. When it was found that thymectomy in successive generations of parent rats resulted in retarding the growth of their offspring, it seemed desirable to determine if this effect could be overcome by the administration of thymus extract (Hanson) to the thymectomized parent rats (2, 3). Five pairs of albino rats (Wistar strain) of known parentage were selected from the normal Stock animals of the Philadelphia Institute for Medical Research. Three pairs were thymectomized at the age of 21 days by the method described in an earlier communication, mated, and at 30 days started on daily intraperitoneal injections of 1 cc. of thymus extract (2). The remaining 2 pairs were subjected to the operative technique concerned i...
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