Abstract
It might be expected that the composition of enamel would affect susceptibility to caries but this is difficult to investigate for several reasons. In particular, since caries begins at small imperfections in the enamel, it may be that it is the composition at these sites, rather than of the enamel as a whole, which affects the resistance of the tooth. No differences have been established in human enamel related to caries-resistance (except the fluoride content in high fluoride areas) although a number of suggestions have been made. Animal experiments suggest that the P CO 3 ratio, the carbohydrate content or the presence of certain trace elements might be related to caries but these points have not been thoroughly investigated in man.
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