Abstract
Marrubium vulgare (Family: Lamiaceae) was used traditionally in the treatment of dyspeptic complains, pulmonary infections, cough, rheumatoid arthritis, night blindness, loss of appetite, as cholagogue, purgative, diuretic, bitter tonic, carminative and appetizer. The phytochemical analysis revealed that the plant contained alkaloids, sterols, steroids, terpenoids (diterpene), saponins, flavonoid, catecholic tannins, anthocyans, phenolic compounds and many other bioactive ingredients. The pharmacological investigations showed that the plant exerted anti-inflammatory, antiedematogenic, analgesic, antioxidant, antimicrobial, antidiabetic, cardiovascular hypolipidemic, antispasmodic and many other biological effects. This review discussed the bioactive contents and pharmacological activities of Marrubium vulgare.
Highlights
IntroductionPlants generally produce many secondary metabolites which are bio-synthetically derived from primary metabolites and constitute an important source of chemicals which are used as pharmaceuticals, agrochemicals, flavours, fragrances, colours, biopesticides and food additives
The phytochemical analysis revealed that the plant contained alkaloids, sterols, steroids, terpenoids, saponins, flavonoid, catecholic tannins, anthocyans, phenolic compounds and many other bioactive ingredients
Plants generally produce many secondary metabolites which are bio-synthetically derived from primary metabolites and constitute an important source of chemicals which are used as pharmaceuticals, agrochemicals, flavours, fragrances, colours, biopesticides and food additives
Summary
Plants generally produce many secondary metabolites which are bio-synthetically derived from primary metabolites and constitute an important source of chemicals which are used as pharmaceuticals, agrochemicals, flavours, fragrances, colours, biopesticides and food additives. Marrubium vulgare (Family: Lamiaceae) was used traditionally in the treatment of dyspeptic complains, pulmonary infections, cough, rheumatoid arthritis, night blindness, loss of appetite, as cholagogue, purgative, diuretic, bitter tonic, carminative and appetizer. The phytochemical analysis revealed that the plant contained alkaloids, sterols, steroids, terpenoids (diterpene), saponins, flavonoid, catecholic tannins, anthocyans, phenolic compounds and many other bioactive ingredients. The pharmacological investigations showed that the plant exerted anti-inflammatory, antiedematogenic, analgesic, antioxidant, antimicrobial, antidiabetic, cardiovascular hypolipidemic, antispasmodic and many other biological effects. This review will highlight the bioactive contents and pharmacological activities of Marrubium vulgare. The current review will highlight the bioactive contents and pharmacological activities of Marrubium vulgare. Synonyms Marrubium apulum, Marrubium ballotoides, Marrubium germanicum, Marrubium hamatum, Marrubium uncinatum, Marrubium vaillantii, Marrubium vulgare subsp. Caucasicum, Marrubium vulgare var. gossypinum, Marrubium vulgare var. lanatum, Marrubium vulgare var. microphyllum and Marrubium vulgare var. oligodon[1]
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