Abstract
The benefits and threats of research partnerships with industry
Highlights
Partnership with industrial sponsors of research carries potential threats both to human subject protection and to research integrity
To the extent that researchers have a financial interest in the success of the research, such as an equity interest in the sponsor, or if the researcher has come to rely upon the sponsor for research funding or for personal income, the researcher has financial interests that substantially align with those of the sponsor; that is, for a successful project with adequate recruitment and positive results
Institutions that have come to rely on industry-sponsored research for overhead payments and other amounts that support the broader research enterprise may fail to provide adequate oversight to ensure appropriate research practices
Summary
Are surrogate markers adequate to assess cardiovascular disease drugs? JAMA 1999, 282:790-795. Are surrogate markers adequate to assess cardiovascular disease drugs? 8. Psaty BM, Weiss NS, Furberg CD, Koepsell TD, Siscovick DS, Rosendaal FR, Smith NL, Heckbert SR, Kaplan RC, Lin D, et al: Surrogate end points, health outcomes, and the drugapproval process for the treatment of risk factors for cardiovascular disease. 9. Marshall M, Lockwood A, Bradley C, Adams C, Joy C, Fenton M: Unpublished rating scales: a major source of bias in randomised controlled trials of treatments for schizophrenia.
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