Abstract
Improved enantioselectivity was achieved in the baker's yeast reduction of the 1-acetoxy-2-alkanone derivatives by the addition of a sulfur compound such as l-cysteine and phenyl vinyl sulfide. The reaction rate of the baker's yeast reduction was accelerated using a sulfur compound as an additive. The migration of the acetyl group and the hydrolysis of the acetoxy group of the substrate was suppressed using a sulfur compound.
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