The axonal transport of ⊖ III-tubulin is altered in both branches of sensory axons after injury of the rat sciatic nerve

Abstract

We have analyzed the axonal transport of β III-tubulin in the central (dorsal root) and peripheral (sciatic nerve) branches of sensory axons after injury of the sciatic nerve. Our finding that the relative amount of β III-tubulin transported in slow component b (SCb) is increased in both axonal branches does not support the generally accepted hypothesis that the transport of cytoskeletal proteins is altered in the peripheral, but not the central branch after injury of the sciatic nerve.