Abstract
The aversive properties of naloxone-precipitated morphine withdrawal from acutely administered morphine were assessed following a single conditioning trial using both the place conditioning and the taste conditioning paradigm. In both paradigms, the aversive properties of naloxone-precipitated morphine withdrawal were evident up to 48 h after a single injection of morphine. In neither paradigm did naloxone treatment alone produce an aversion after a single conditioning trial. These results suggest that a single morphine exposure produces long-lasting effects that persist at least 48 h beyond the agonist effects of the opiate.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
