The associations between different sleep patterns and osteoporosis based on the Osteoporosis Self-Assessment Tool for Asians

Shaojun Wu,Hongmei Yang,Yingxian Sun,Zhao Li,Shasha Yu,Xiaofan Guo,Ying Zhou,Pengbo Wang,Liqiang Zheng,Guozhe Sun

doi:10.1007/s11657-020-00828-y

Abstract

SummaryBased on the use of Osteoporosis Self-Assessment Tool for Asians (OSTA) to assess osteoporosis risk, we found that short sleep duration and taking a daytime nap had an increased risk of osteoporosis.PurposeTo explore the associations between different sleep patterns with osteoporosis.Methods3659 postmenopausal women (average age of 60 years) were divided into low, middle, and high osteoporosis risk categories based on the Osteoporosis Self-Assessment Tool for Asians (OSTA). After having collected by a standard questionnaire, total and nocturnal sleep duration was collapsed to form categories of ≤ 6 h, > 6 h and ≤ 7 h, > 7 h and ≤ 8 h, > 8 h and ≤ 9 h, > 9 h, and daytime nap duration of 0 h and > 0 h.ResultsAs a categorical variable, the total sleep duration of ≤ 6 h per day (OR = 1.34, 95% CI 1.04–1.72), nocturnal sleep duration of ≤ 6 h per night (OR = 1.65, 95% CI 1.24–2.18), and taking a daytime nap (OR = 1.33, 95% CI 1.09–1.64) had higher osteoporosis risk after adjustment for covariates. As a continuous variable, after the adjustment for covariates, both longer total (OR = 0.86, 95% CI 0.78–0.94) and nocturnal sleep duration (OR = 0.83, 95% CI 0.76–0.91) had lower risk of osteoporosis risk while taking longer daytime nap (OR = 1.10, 95% CI 1.02–1.19) had higher osteoporosis risk.ConclusionsPostmenopausal women with both short total and nocturnal sleep duration (6 h or less) and taking a daytime nap had increased osteoporosis risk as assessed by OSTA.

Highlights

Osteoporosis is a systemic bone disease characterized by low bone mineral density (BMD) and micro-architectural deterioration of bone tissue that affects 200 million people worldwide [1]
A series of epidemiological studies had been performed to explore the association between sleep duration and osteoporosis, of which some [8,9,10] stated that long sleep duration (8 h or more per day) might be associated with a higher risk of osteoporosis and some [11,12,13] suggested that those with short sleep duration were more likely to have higher risk of osteoporosis
Hypertension, currently smoking, currently drinking, and regular physical activity were more often found in individuals with high osteoporosis risk (65.9%, 33.7%, 5.6%, and 30.0%, respectively) while those who were diagnosed with diabetes mellitus were prone to low osteoporosis risk

Summary

Introduction

Osteoporosis is a systemic bone disease characterized by low bone mineral density (BMD) and micro-architectural deterioration of bone tissue that affects 200 million people worldwide [1]. The commonly unrecognized fracture caused by osteoporosis is often associated with increased mortality, morbidity [2], and health costs [3]. Height, lifestyle patterns, vitamin D intake, and some other potential variables are widely recognized as the risk factors for osteoporosis [4]. A fundamental physiological activity and closely related to circadian rhythms, was found to be involved with bone metabolism [5,6,7]. Swanson et al [14] reported that between sleep duration and osteoporosis risk in older postmenopausal women, there was no significant association

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