The associations between anthropometric measurements and left ventricular structure and function: the Echo-SOL Study.

Abstract

SummaryObjectiveThe objective of this study is to determine associations between anthropometry and echocardiographic measures of cardiac structure and function in Hispanic/Latinos.MethodsA total of 1,824 participants from ECHO‐SOL were included. We evaluated associations between echocardiographic measures of left ventricular structure and function and anthropometric measures using multivariable‐adjusted linear and logistic regression models adjusting for traditional cardiovascular risk factors.ResultsThe mean age was 56 ± 0.17 years, 57% were women. The mean body mass index (BMI) was 30 ± 9.4 kg m−2, waist circumference (WC) was 100 ± 18 cm, and waist‐to‐hip ratio (WHR) was 0.93 ± 0.15. Adjusted analysis showed that 5‐unit increment in BMI and 5‐cm increase in WC was associated with 3.4 ± 0.6 and 1.05 ± 0.05 g m−2.7 (p < 0.05 for both) higher left ventricular (LV) mass index, respectively. Similarly, 0.1‐unit increment in WHR was associated with 2.0 ± 0.16 g m−2.7 higher LV mass index (p < 0.01). WHR was associated with 0.22 ± 0.08% decrease in ejection fraction (p < 0.05). Concomitantly, 5‐unit increment in BMI and WC was associated with increased odds of abnormal LV geometry (odds ratio 1.40 and 1.16, p = 0.03 and <0.01, respectively); 0.1‐unit increment in WHR was associated with increased odds of abnormal LV geometry (odds ratio 1.51, p < 0.01).ConclusionsAmong Hispanic/Latinos, higher anthropometric measures were associated with adverse cardiac structure and function.