Abstract
High selenium concentrations were associated with cardiovascular diseases, type 2 diabetes, and central nervous disorders. The author examined the relation of serum selenium concentration with serum lipids levels with the use of the National Health and Nutrition Examination Survey (NHANES) 2017-2018. 759 adults aged more than 20 years old from NHANES 2017-2018 were examined in the analysis. Serum selenium was measured by mass spectrometry. Triglyceride, HDL cholesterol, and total cholesterol were measured through enzymatical methods. LDL cholesterol was calculated then. Comparing Q4 to Q1 of serum selenium, the multivariable adjusted average differences (95% CI) in triglyceride, HDL cholesterol, LDL cholesterol, and total cholesterol were 21.3 mg/dL (9.1, 33.4 mg/dL), 2.3 mg/dL (-0.6, 5.2 mg/dL), 6.3 mg/dL (-1.3, 13.9 mg/dL), 12.8 (95% CI: 4.2, 21.5 mg/dL), respectively. Hence, The increasing serum selenium concentration is associated with increasing triglyceride, total cholesterol, HDL cholesterol, and LDL cholesterol among US adults.
Highlights
Selenium is incorporated into selenoproteins that have antioxidant effects1
The author aims to find out the relationship between the serum selenium concentration and the lipid levels
2.2 Serum lipids Total cholesterol concentrations and HDL cholesterol concentrations were measured by Advanced Research and Diagnostic Laboratory (ARDL), University of Minnesota, using Roche Cobas 60008
Summary
Selenium is incorporated into selenoproteins that have antioxidant effects. The discovery of the association between many diseases and selenoproteins has drawn considerable attention. Increasing selenium levels were related higher prevalence of type 2 diabetes, cardiovascular diseases, and central nervous disorders2345. A study conducted in 2010 found that in the US, the whole population has selenium intake over 55 μg/d, the selenium intake of the Recommended Dietary Allowance. Another study stated that in the United States, almost all US adults have serum selenium concentration over 95 ng/mL, well beyond the maximum threshold to activate glutathione peroxidases. Since selenium has gained much interest in treating certain diseases, it is necessary to first evaluate the effect of serum selenium on the nutrition profile. The author aims to find out the relationship between the serum selenium concentration and the lipid levels
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
