Abstract
Methodology Ninety consecutive patients at a university hospital in Manaus, Amazonas were included in this study. Eighty-six (95.6%) had type 2 diabetes, 66.7% were female, mean age was 56.2±12.8 yrs.-old and mean time of diabetes diagnosis was 11.5±9.5 yrs. They were evaluated using Michigan Neuropathy Screening Instrument (MNSI) and the clinical component of the Michigan Diabetic Neuropathy Score (MDNS). This component evaluates vibratory, painful and tactile sensitivities. Subjects who scored 7 or more on this component of the MDNS were considered as having PDN (Feldman et al., 1994). MNSI and MDNS clinical component scores were analyzed according to lipid profile and statin use.
Highlights
Peripheral neuropathy is a common complication of diabetes mellitus, usually manifesting as axonal sensitivemotor symmetric polyneuropathy
In the EURODIAB study, total cholesterol and triglycerides were associated to peripheral diabetic neuropathy (PDN)
When considering only the 65 (72.2%) patients with serum urea below 50 mg/dL, there was a positive correlation between total cholesterol and Michigan Diabetic Neuropathy Score (MDNS) (r=0.2580, p
Summary
The association of dyslipidemia and peripheral diabetic neuropathy: the influence of urea. Patrícia Carvalho Machado Aguiar*, Marcus Vinícius Della Coletta, Jean Jorge Silva de Souza. From 20th Brazilian Diabetes Society Congress Porto Alegre, Brazil. From 20th Brazilian Diabetes Society Congress Porto Alegre, Brazil. 11-18 November 2015
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