Abstract

The Association between Subclinical Hypothyroidism and Components of Metabolic Syndrome

Highlights

  • The Metabolic Syndrome (Mets) includes central obesity, Hyperglycemia Plus Insulin Resistance (IR), Hypertension (HTN), Dyslipidemia [1]

  • Our study suggests that Subclinical Hypothyroidism (SCH) might be a risk factor for Mets and its components

  • Further investigations are needed to evaluate the mechanism of this correlation

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Summary

Introduction

The Metabolic Syndrome (Mets) includes central obesity, Hyperglycemia Plus Insulin Resistance (IR), Hypertension (HTN), Dyslipidemia [1]. There are several studies about the correlation between thyroid function and components of Mets, but the results are disputed. A cross-sectional study of 1581 Euthyroid subjects found that there was positive correlation between Thyroid Stimulating Hormone (TSH) and index of IR as well as Triglyceride (TG) [2]. About one sixth of the Mets patients in Turkey were found to have Subclinical Hypothyroidism (SCH) [3]. Thyroid hormones are major regulatory hormones and may be associated with metabolic syndrome [4,5]. The burden of thyroid diseases in the general population and patients with Metabolic Syndrome (Mets) is enormous. The present study was an effort to investigate the association between Subclinical Hypothyroidism (SCH) and components of Mets in a selected group of patients with Mets in Saudi Arabia

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