Abstract

BackgroundResearch highlighted that Stressful Life Events have high incidence among infertile patients and significant impact on physical and medical parameters related to reproductive functions, but their potential role among factors influencing the infertile patients’ perception of fertility-related Quality of Life (QoL) has not been explored. The present study aims to investigate the associations of Stressful Life Events (Stressful events in the family of origin, In family pre-existing pregnancy difficulties, Health problems in childhood) with perceived fertility-related QoL in women attending infertility treatments, examining the potential moderating role of adopted coping strategies and perceived couple’s dyadic adjustment.MethodsA questionnaire consisting of Socio-demographics and Infertility-related characteristics, Stress-inducing events in the couples’ lives Questionnaire (FLS), Coping Orientations to Problem Experienced (COPE), Dyadic Adjustment Scale (DAS), and Core and Treatment subscales of Fertility Quality of Life (FertiQoL) was administered to 266 women attending infertility treatments. A descriptive correlational design with cross-sectional comparison was used. Results Logistic Regression Analyses after adjusting for socio-demographic and infertility-related characteristics revealed that women who reported Stressful events in the family of origin and In family pre-existing pregnancy difficulties were more likely to report lower levels of perceived Core QoL, while women who reported Health problems in childhood were more likely to report lower levels of perceived Treatment QoL. Couple’s dyadic adjustment and specific coping strategies were significantly associated with perceived Core and Treatment QoL and they also significantly moderated the associations between stressful life events and perceived QoL.ConclusionsData provided original evidence on the strong association between stressful life events and perceived fertility-related QoL also highlighting individual and couples’ resources to define counselling interventions with women attending infertility treatments.

Highlights

  • Research highlighted that Stressful Life Events have high incidence among infertile patients and significant impact on physical and medical parameters related to reproductive functions, but their potential role among factors influencing the infertile patients’ perception of fertility-related Quality of Life (QoL) has not been explored

  • Considering infertility research, several studies showed that the presence of stressful events in the family of origin, in family pre-existing pregnancy difficulties, and health problems in childhood is frequently reported in the biographical background of infertile patients [43,44,45], revealing a significant impact on relevant physical and medical parameters related to the reproductive functions, such as menstrual cycle regularity [46], semen quality [47], and pregnancy outcome after In Vitro Fertilization (IVF) [48,49,50]

  • Considering the significant role exerted by individual resources [26, 27, 51,52,53,54,55], and by relational resources [3,4,5, 29, 31] invested in dealing with infertility, the present study aims at testing the potential moderating role of adopted coping strategies and of perceived couple’s dyadic adjustment in the relationship between experienced Stressful Life Events and perceived levels of Fertility-related Core and Treatment QoL

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Summary

Introduction

Research highlighted that Stressful Life Events have high incidence among infertile patients and significant impact on physical and medical parameters related to reproductive functions, but their potential role among factors influencing the infertile patients’ perception of fertility-related Quality of Life (QoL) has not been explored. Considering infertility research, several studies showed that the presence of stressful events in the family of origin (e.g., divorce, financial problems, deaths, maltreatment), in family pre-existing pregnancy difficulties (e.g., unwanted child, stillborn children, abortion), and health problems in childhood (e.g., injuries, illness, hospitalization) is frequently reported in the biographical background of infertile patients [43,44,45], revealing a significant impact on relevant physical and medical parameters related to the reproductive functions, such as menstrual cycle regularity [46], semen quality [47], and pregnancy outcome after In Vitro Fertilization (IVF) [48,49,50]

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