Abstract
BackgroundRight ventricular (RV) function has been found to be a major factor of exercise capacity in patients with heart failure. However, the role of RV function in exercise capacity in healthy subjects has not been well studied. This study aims to validate the role of RV strain derived from speckle tracking echocardiography for exercise capacity for health check-up subjects.MethodsThis study prospectively recruited subjects from a routine health examination. All of them were symptom free. RV function represented by RV strain was derived from speckle tracking echocardiography in addition to traditional echocardiography parameters. Functional capacity was determined by a symptom limited treadmill exercise test with the Bruce protocol.ResultsAmong 164 recruited subjects (age 52.2 ±9.2 years, 66.4% male), 32 subjects represented impaired functional capacity (MET<8), which was significantly correlated with age, left ventricular mass index, left ventricular filling pressure (E/e’), global longitudinal strain of the left ventricle (LVGLS) (-16.0±2.5% vs. -18.9±3.8%, p < 0.001) and RV free wall strain (RVLS_FW) (-17.0±4.9% vs. -21.9±3.2%, p <0.001). After multivariate logistic regression, RVS_FW was an independent predictor for impaired functional capacity (OR 1.62, CI 1.32–1.98; p <0.001).ConclusionsIn conclusion, RV strain is independently associated with exercise capacity for health check-up subjects. RV function is an important factor for functional capacity.
Highlights
Exercise capacity, as reflecting cardiac function, has been known as a powerful predictor of mortality among patients with various diseases [1]
This study aims to validate the role of Right ventricular (RV) strain derived from speckle tracking echocardiography for exercise capacity for health check-up subjects
Among 164 recruited subjects, 32 subjects represented impaired functional capacity (MET
Summary
As reflecting cardiac function, has been known as a powerful predictor of mortality among patients with various diseases [1]. The association between exercise capacity and traditional echocardiographic parameters remains indeterminate, emerging imaging modalities can help distinguish patients with preserved or impaired exercise capacity [2,3]. Among these modalities, speckle tracking echocardiography (STE) has been used to detect occult myocardial dysfunction that may result in reduced exercise capacity [4,5]. We aim to identify the role of STE in detecting subtle myocardial dysfunction and its associated changes of exercise capacity in health check-up subjects. This study aims to validate the role of RV strain derived from speckle tracking echocardiography for exercise capacity for health check-up subjects
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
