The association between quarter somatic-cell counts and clinical mastitis in three British dairy herds

Abstract

The association between quarter somatic-cell counts (QSCCs) of milk and the risk of clinical mastitis (CM) was investigated in a 1-year study on three dairy herds in Somerset, UK. The three herds had 95–130 milking cows and an annual mean bulk milk somatic-cell count (BMSCC) of <150×10 3 cells/ml. The farms were visited every 4–6 weeks at morning milking when quarter-milk samples were collected. The farmers recorded all cases of CM and were trained to collect sterile milk samples from affected quarters, before treatment for bacteriology. The three herds had CM incidence rates of 25.4, 55.2, and 67.6 quarter-cases per 100 cow-years. Escherichia coli and Streptococcus uberis were cultured from approximately 50% of cases. QSCC was categorised and the risk of CM occurring in the month after the QSCC was examined using multilevel models to account for the correlated nature of the dependent data. Three models were developed: one for all cases of CM, one for those caused by coliforms and one for those caused by S. uberis. When all cases of CM were considered, quarters with somatic-cell count (SCC) 21–100×10 3 cells/ml had reduced odds (OR=0.60, P=0.06) and quarters with SCC >200×10 3 cells/ml has over three time the odds (OR=3.7, P<0.01) of CM compared with QSCC 1–20×10 3 cells/ml. When only coliform CM were investigated, quarters with SCC 6–200×10 3 cells/ml had reduced odds of coliform CM (OR=0.47, P=0.04) compared with QSCC 1–5×10 3 cells/ml, and SCC >200×10 3 cells/ml were not significantly different from the baseline. Finally, when S. uberis CM were investigated, quarters with SCC >200×10 3 cells/ml had more than three times the odds of S. uberis CM compared with QSCC 1–20×10 3 cells/ml (OR=3.73, P<0.01). QSCC <21×10 3 and >200×10 3 cells/ml are associated with increased odds of CM in the following 4–6 weeks; this association may be pathogen specific.