Abstract

BackgroundHyperlipidemia and hypertension are well-established risk factors for recurrent cardiovascular events among patients with ischemic heart disease (IHD). Despite national recommendations, concordance with guidelines for LDL cholesterol and blood pressure remains inadequate. The objectives of this study were to 1) determine concordance rates with LDL cholesterol and BP recommendations; and 2) identify patient factors, processes and structures of care associated with guideline concordance among VA IHD patients.MethodsThis was a cross sectional study of veterans with IHD from 8 VA hospitals. Outcomes were concordance with LDL guideline recommendations (LDL<100 mg/dl), and BP recommendations (<140/90 mm Hg). Cumulative logit and hierarchical logistic regression analyses were performed to identify patient factors, processes, and structures of care independently associated with guideline concordance.ResultsOf 14,114 veterans with IHD, 55.7% had hypertension, 71.5% had hyperlipidemia, and 41.6% had both conditions. Guideline concordance for LDL and BP were 38.9% and 53.4%, respectively. However, only 21.9% of the patients achieved both LDL <100 mg/dl and BP <140/90 mm Hg. In multivariable analyses, patient factors including older age and the presence of vascular disease were associated with worse guideline concordance. In contrast, diabetes was associated with better guideline concordance. Several process of care variables, including higher number of outpatient visits, higher number of prescribed medications, and a recent cardiac hospitalization were associated with better guideline concordance. Among structures of care, having on-site cardiology was associated with a trend towards better guideline concordance.ConclusionGuideline concordance with secondary prevention measures among IHD patients remains suboptimal. It is hoped that the findings of this study can serve as an impetus for quality improvement efforts to improve upon secondary prevention measures and reduce the morbidity and mortality of patients with known IHD.

Highlights

  • Hyperlipidemia and hypertension are well-established risk factors for recurrent cardiovascular events among patients with ischemic heart disease (IHD)

  • Our objectives were to assess guideline concordance for secondary prevention care based on low-density lipoprotein (LDL) cholesterol and blood pressure control and to identify specific patient, processes of care and structures of care factors associated with guideline concordance

  • When guideline concordance was based on both achievement of LDL

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Summary

Introduction

Hyperlipidemia and hypertension are well-established risk factors for recurrent cardiovascular events among patients with ischemic heart disease (IHD). Concordance with guidelines for LDL cholesterol and blood pressure remains inadequate. Prior studies have found significant gaps in the achievement of nationally recommended low-density lipoprotein (LDL) cholesterol and blood pressure (BP) levels [2,3,4,5]. The risk of a future IHD event, according to the Framingham risk estimates, is based on multiple factors including blood pressure level, cholesterol level, smoking status, and age [8]. Given the high absolute risk of recurrent cardiovascular events among IHD patients, studies addressing secondary prevention care should encompass multiple risk factors (e.g., hyperlipidemia and hypertension). Prior studies assessing guideline concordance with secondary prevention measures have focused mainly on either hyperlipidemia or hypertension alone within any one study

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