Abstract
Polycystic ovary syndrome (PCOS) commonly occurs in reproductive-age females. It elevates the hormonal levels, creates an imbalance in the metabolic system, and affects their reproductive system too. A number of studies have been conducted on PCOS, and it has been diagnosed together with several dermatological conditions. In this paper, we attempt a traditional review to study the relationship between PCOS and its cutaneous manifestations the patients are predisposed to. To uncover this association, we gathered information from English-language articles on the Pubmed database using six keywords. Materials were also collected from studies done on animal models, which helped in putting down all the data together and interlinking them with other studies. From this data collection, it is ultimately concluded that the association between PCOS and dermatological conditions is a very intricate interconnecting network comprising many factors, such as inflammation, genetics, and hormonal. This study raises some questions that are still unanswered. We believe further research is needed to uncover the various facts about this disease and its associations, in order to make its management more effective. As there is a strong association between PCOS and certain dermatological disorders, it is recommended to develop a questionnaire that should be distributed to every woman who presents to dermatology departments with symptoms that are linked to PCOS, as it will help in diagnosing the condition at an early stage.
Highlights
BackgroundPolycystic ovary syndrome (PCOS), known as Stein-Leventhal syndrome, affects 6-10% women of fertile age group [1]
In a study conducted by Botchkarev VA, it was concluded that bone morphogenetic protein (BMP) is included in the homeostasis of skin epidermis and development of hair follicles, interceding its activity through a mitogen-activated protein (MAP) kinase pathway, with a prenatal
The main motive of this study was to explore the link between PCOS and its cutaneous manifestations pertaining to the dermato-endocrinology field
Summary
Polycystic ovary syndrome (PCOS), known as Stein-Leventhal syndrome, affects 6-10% women of fertile age group [1]. It is the most prevalent heterogeneous condition, with cardinal features consisting of hyperandrogenism and reproductive and metabolic dysfunction. · Presence of hyperandrogenism, oligomenorrhea, and polycystic ovary. PCOS presents with a wide spectrum of common dermatological manifestations, such as hirsutism, acne, seborrheic dermatitis (SD or seborrhea), and androgenetic alopecia (AGA). These conditions can present alone or alongside other features of virilization. An additional two cases with mucosal pigmentation suggesting Peutz-Jegher syndrome have been reported to have an association with PCOS [5,6,7,8]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
