The association between lichen planus and hepatitis C virus infection: A case control study

G Rai Subodha Kumar,Rangaswamy Umadevi,Nagesha Parvathi,Rangegowda Suresh,Nirvanappa Vinay

doi:10.7241/ourd.2021e.85

Abstract

Background: The incidence of Hepatitis C virus (HCV) infection among patients with Lichen planus (LP) varies considerably. There is also lack of data in Indian population. Due to these variation, this study is to assessing the prevalence of HCV infection among patients with CLP in Hassan Karnataka. Methods: 135 clinically diagnosed cases of Lichen planus more than 18 years of age will be included as cases.147 patients having skin diseases other than lichen planus will be included as controls. Details of the patients personal history and family history,medical history and blood transfusion history will be collected. Detection of antibodies against HCV (anti-HCV) by enzyme-linked immunosorbent assay (ELISA). Results: Anti-HCV antibodies were found in 3(2.2%) patients of the case group and 1(0.7%) in control group. P value is 0.274, not statistically significant. Conclusion: Currently, there is no evidence confirming the relationship between HCV infection and CLP in Hassan Karnataka. However, there is a need for further research on larger groups of

Highlights

Lichen Planus (LP) is a chronic inflammatory disorder with involvement of skin, oral and genital mucosa, scalp, and nail appendages [1]
A papulosquamous disease that has derived its nomenclature from the Greek word “Leichen” as it resembled Lichens moss growing on the rock and Planus that stands for flat1
This study is to assessing the prevalence of Hepatitis C virus (HCV) infection among patients with cutaneous LP (CLP) in Hassan Karnataka

Summary

Introduction

Lichen Planus (LP) is a chronic inflammatory disorder with involvement of skin, oral and genital mucosa, scalp, and nail appendages [1]. A papulosquamous disease that has derived its nomenclature from the Greek word “Leichen” as it resembled Lichens moss growing on the rock and Planus that stands for flat. A papulosquamous disease that has derived its nomenclature from the Greek word “Leichen” as it resembled Lichens moss growing on the rock and Planus that stands for flat1 It was first described by Dr Wilson in 1869. The incidence of Hepatitis C virus (HCV) infection among patients with Lichen planus (LP) varies considerably. There is lack of data in Indian population Due to these variation, this study is to assessing the prevalence of HCV infection among patients with CLP in Hassan Karnataka. Results: Anti-HCV antibodies were found in 3(2.2%) patients of the case group and 1(0.7%) in control group. There is a need for further research on larger groups of

Methods

Results

Discussion

Conclusion