Abstract
Background: Indoor air pollution is still considered one of the leading causes of morbidity and mortality worldwide. We aimed to investigate the potential association between indoor particulate matter (PM) and fasting clinic blood pressure in adult Australians. Methods: Sixty-three participants residing within the Perth metropolitan area were studied. Participants were aged between 18 and 65 years and free of major medical conditions. We conducted 24-h monitoring of residential PM concentrations, including the size fractions PM1, PM2.5, PM4, and PM10. All participants attended a clinical assessment at Curtin University following a 10–12 h overnight fast. Results: In this study we found that PM1 and PM2.5 were significantly associated with heart rate: a one interquartile range (IQR) increase in PM1 or PM2.5 was associated with a 4–6 beats per minute (bpm) increase in heart rate. Both PM10 and total PM exposure had a significant impact on systolic blood pressure (SBP): a one IQR increase in PM10 and total PM were associated with a 10 mmHg (95% CI: 0.77–20.05) and 12 mmHg (2.28–22.43 mmHg) increase in SBP, respectively. Conclusion: The study findings provide additional support to the thesis that indoor air pollution is an important modifiable factor in the risk of hypertension.
Highlights
Despite decades of progress in both the prevention and the management of individuals with elevated blood pressure (BP), suboptimal BP remains the single, most important contributor to the global burden of cardiovascular diseases [1,2]
The objective of this study was to investigate the potential association between different indoor particulate matter (PM) size fractions and both BP and heart rate (HR) outcomes in adult Australians
In this study we examined the potential association between chronic exposures, not acute exposures, to air pollutants and a chronic condition of altered resting BP
Summary
Despite decades of progress in both the prevention and the management of individuals with elevated blood pressure (BP), suboptimal BP remains the single, most important contributor to the global burden of cardiovascular diseases [1,2]. Ambient aerosols in urban environments usually originate predominantly from fossil fuel burning, car emissions, resuspension, and chemical and thermodynamic processes, but can come from long range transport [8]. Due to their diverse sources, airborne particles span a large size range, from a few. Results: In this study we found that PM1 and PM2.5 were significantly associated with heart rate: a one interquartile range (IQR) increase in PM1 or PM2.5 was associated with a 4–6 beats per minute (bpm) increase in heart rate Both PM10 and total PM exposure had a significant impact on systolic blood pressure (SBP):
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