The Association between Dietary Vitamin C/E and Gestational Hypertensive Disorder: A Case-Control Study.

Abstract

A case-control study of 10,228 gestational women was conducted in Lanzhou, China, between 2010 and 2012. This study aimed to evaluate the associations between the risk of gestational hypertensive disorders and dietary intake of vitamin C/E. Among this study's participants, 5.41% (n=553) were diagnosed with gestational hypertensive disorders. Of these disorders, 69.44% (n=384) were preeclampsia and 30.56% (n=169) were considered to be gestational hypertension. After adjustment for confounding variables and other relevant dietary nutrients, no association was found between the risk of gestational hypertensive disorders and dietary intake of vitamin C, vitamin E, copper or manganese before or during pregnancy. However, zinc and selenium intake was associated with the decrease risk of gestational hypertensive disease during different stages of pregnancy (p<0.05). Gestational dietary intake of zinc and selenium can significantly decrease the risk of gestational hypertensive disorders. No association was found between gestational hypertensive disorders and vitamin C, vitamin E, copper or manganese intake.