Abstract
Background: Central obesity and Irritable Bowel Syndrome (IBS) are common medical conditions with similar etiologic mechanisms. There are limited studies to evaluate the association between obesity, especially central obesity; with IBS. Establishing such association is important in the management of IBS. Objective: To evaluate the association between central obesity and IBS in Iraqi patients using Waist-to-Height ratio (WtHR) as an index of central obesity. Patients and Methods: Central obesity defined by Waist-to-Height ratio > 0.5. Inclusion and exclusion criteria for diagnosing IBS were used. A case-control study was performed at AL-Nuaman Teaching Hospital in the period from January 2015 to December 2015, Comparing Waist-to-Height ratio (WtHR) between 75 patients (with IBS) and 130 controls (without IBS) to assess the association between central obesity and IBS. Chi-square test with 95% confidence was used to evaluate association between central obesity and IBS, and Odds ratio (OR) for central obesity was determined. Results: There is significant association between central obesity and IBS, x2 (1) = 36.2, P Conclusion: Central obesity is significantly associated with IBS and may be regarded as a risk factor for IBS.
Highlights
Irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder with a prevalence of up to 45% [1]
Prevalence of central obesity in IBS group was more than 3 times in non- IBS group (Table 1), and most of control group have no central obesity (Figure 1)
Central obesity was significantly associated with IBS (odds ratio (OR), 6.4; 95% confidence interval [CI], 3.4 to 12.03)
Summary
Irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder with a prevalence of up to 45% [1]. Obesity is a common chronic endocrine disorder associated with many diseases including those related to GIT mainly GERD [5,6,7], but there are limited studies to prove association with IBS. There are limited studies to evaluate the association between obesity, especially central obesity; with IBS. Objective: To evaluate the association between central obesity and IBS in Iraqi patients using Waist-to-Height ratio (WtHR) as an index of central obesity. A case-control study was performed at AL-Nuaman Teaching Hospital in the period from January 2015 to December 2015, Comparing Waist-to-Height ratio (WtHR) between 75 patients (with IBS) and 130 controls (without IBS) to assess the association between central obesity and IBS.
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