The assessment of fertilization and embryonic development using testicular spermatozoa among presumed histopathology in testicular biopsy from non-obstructive azoospermia (NOA)

Abstract

Fertilization and pregnancies can be obtained with spermatozoa recovered from the seminiferous tubules. Sertoli cell only syndrome (SCOS), maturation arrest (MA), and hypospermatogenesis (HS), and, with or without focal spermatogenesis are the commonest histological patterns of patients with non-obstructive azoospermia (NOA). To our knowledge, no study has specifically examined the results of intracytoplasmic sperm injection (ICSI) in SCOS, MA, and HS patients. The aim of this study is to assess sperm retrieval rates (SRR) by microdissection testicular sperm extraction (micro-TESE), fertilization rate, and embryonic development among patients with presumed SCOS, MA, and HS in testicular biopsy in those couples whom spermatozoa were obtained.