Abstract

We examined the effects of occupational ionizing radiation exposure in radiology workers on bone mineral density and serum alkaline phosphates (ALP) levels. 49 subjects, aged between 21-48 years (33.86 years), working in the department of radiology were enrolled to this study. 26 subjects were female and 23 were male. Control group consisted of 40 healthy subjects aged between 22-49 years (mean 33.83) who had never been exposed to radiation; 21 of these were female and 19 male. Venous blood samples were obtained from the radiology workers and control group and serum alkaline phosphatase levels analysis of samples were performed. The bone mineral density (BMD) was assessed in the spine and the hip with a dual-energy x-ray absorptiometry (DEXA) instrument. T-scores of radiology workers was lower than control group significantly (P 0.05). T-scores of the men at the control group were higher than the women’s however the case was just the opposite for the work group. In radiology workers exposed to long-term low-dose ionizing radiation has negative effect on bone mineral density and serum ALP levels.

Highlights

  • All cells can be damaged by ionizing radiation, but actively dividing cells are more radiosensitive

  • Even if radiation is in low doses, long-term exposure to radiation decreases bone mineral density

  • We found out that T-scores of radiology workers were significantly lower than the control group (P < 0.01)

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Summary

Introduction

All cells can be damaged by ionizing radiation, but actively dividing cells are more radiosensitive. Received: 10.04.2012, Accepted: 12.03.2013 row stem cells are one of the most radiosensitive cells in the human body [1,2,3]. Bone atrophy and bone fractures increase in patients after exposure to radiation [4,5]. Long-term exposure to low levels of radiation may cause bone damage. Even if radiation is in low doses, long-term exposure to radiation decreases bone mineral density. The aim of this study is finding out the negative effects of exposure to low dose ionize radiation at bone mineral density and serum alkaline phosphates levels of radiology workers

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