Abstract
Background: Neurodegenerative diseases are disorders in which nerve cells start to lose function due to different causes. Like many other illnesses, they are considered to be highly prevalent in the 22 Arabic-speaking countries known to constitute the Arab world. The two most prevalent neurodegenerative disorders are Alzheimer's disease and Parkinson's disease.Aim: The aim of this paper is to assess the amount of research dedicated to neurodegenerative diseases by the Arab countries during a 15-year period, between 2005 and 2019.Methods: The number of publications by each Arab country as well as some non-Arab speaking countries was retrieved from PubMed. Publications in top 10 neuroscience journals were also tracked using the same method with each journal’s name included. The numbers were then normalized with respect to the average population and average gross domestic product (GDP) in each country to eliminate bias.Results: Arab countries were shown to contribute only 1,311 (0.774%) of the 169,330 articles published worldwide on neurodegenerative disorders. These 1,311 also constitute only 0.660% of the 198,869 Arab publications during the indicated period. Saudi Arabia had the highest contribution to these numbers with more than one-quarter the number of publications on neurodegenerative disorders. Approximately one-third of all neurodegenerative disease-related articles were associated with Alzheimer's disease, whereas one-fifth were related to Parkinson's disease. For the top 10 neuroscience journals, only a minimal contribution by Arab countries was noted.Conclusion: Although an increase in the number of articles by the Arab world was noted from 2013 onward, the contribution of the Arab countries on the subject to the number of publications still seems to be insufficient.
Highlights
The Arab world consists of 22 Arabic-speaking countries, concentrated mainly in the Middle East and North Africa
Saudi Arabia had the highest contribution to these numbers with more than one-quarter the number of publications on neurodegenerative disorders
Onethird of all neurodegenerative disease-related articles were associated with Alzheimer's disease, whereas one-fifth were related to Parkinson's disease
Summary
The Arab world consists of 22 Arabic-speaking countries, concentrated mainly in the Middle East and North Africa. Neurodegenerative disorders are diseases where nerve cells start to lose function and die, and proteins accumulate in the brain and other peripheral organs [2]. They are mainly classified according to the deposited protein and the better-known tauopathies, alpha-synucleinopathies, prion diseases, trinucleotide repeat diseases, neuroserpinopathy, ferritinopathy, and cerebral amyloidoses [2]. Alzheimer’s disease is considered to be the most prevalent neurodegenerative disorder constituting 60-80% of all dementia cases, with approximately 24 million people affected with the disease worldwide [4]. They are considered to be highly prevalent in the 22 Arabicspeaking countries known to constitute the Arab world. The two most prevalent neurodegenerative disorders are Alzheimer's disease and Parkinson's disease
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