The AR and ARFI-Based Models Utility of Magnetoencephalography Assisted Diagnosis of Depression

Abstract

This paper is an attempt to distinguish depressed patients from healthy samples mainly by analyzing magnetoencephalogram data of depressed patients and healthy people under different emotional picture stimuli. The following conclusions are mainly drawn: First, the relationship of information storage and condition entropy is obtained firstly through the formula derivation, and the higher the information storage value, the lower the condition entropy. The healthier the biological system, the higher the complexity. Second, the conditional entropy values of the magnetoencephalography channel were mostly higher in the healthy samples than in the depressed patients under the emotional picture stimulation. Accordingly, the conditional entropy values of the frontal region under negative stimulation were lower in depressed patients than in healthy subjects. Third, under both the AR model and the ARFI model, the magnetoencephalogram information storage values were higher in depressed patients than in healthy samples. The difference was more pronounced especially near the frontal regions for both. The variability of the results obtained under the ARFI model was even more pronounced when depressed patients and healthy samples were more discriminated near the left frontal region than the right frontal region, as revealed by the study of line plots of information storage values across left and right frontal regions channels.