Abstract
In this paper, PCA combined with Mass Profiler Professional (MPP) bioinformatics software were used to build the dose-effect relationship of traditional Chinese medicine which based on the overall effect of metabonomics. The dataset from Da Cheng Qi Decoction (DCQD) water extract administrated rats plasma collected by UHPLC-Q-TOF-MS and used to demonstrate this method. The approach was confirmed to be an effective and time-saving tool for describing the dose-effect relationship of traditional Chinese medicine.
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