The application of Sonoclot,a coagulation and platelet function analysis system in cardiopulmonary bypass surgery

Abstract

Objective To explore Sonoclot clinic value observing coagulation and platelet function in 135 cardiopulmonary bypass surgery.Methods 135 cases of cardiopulmonary bypass surgery were taken venous blood before anesthesia,before CPB and protamine administration,respectively.The Sonoclot coagulation and platelet function analysis appliance detected ACT,CR and PF.Meanwhile,the ACT,PT,APTT,FIB and PLT were detected using routine methods.Results The ACT,CR and PF were markedly increased after CPB (P<0.05)using Sonoclot.And also the ACT,PT,APTT,FIB and PLT were markedly increased after CPB (P<0.05)using routine methods.And the ACT value between two methods exited positive correlation.Condusion Sonoclot detecting coagulation and platelet function can replace routine methods. Key words: Sonoclot; Coagulation; Cardiopulmonary bypass